By Eveline S. Litscher, Paul M. Wassarman
This e-book offers a coherent, transparent, and uniform presentation of structural, genetic, molecular, and biochemical details on hand for the zona pellucida area protein family members, which impression pathologies reminiscent of infertility, deafness, and melanoma. in addition it:
- Details information regarding the constitution and serve as of the ZP area in ZPDC-proteins
- Provides illustrations of the association of ZPDC-proteins, the genes that encode the proteins, and examples of mutations within the ZP area that reason diseases
- Speculates as to the evolution of the ZP area and strength therapeutics for ailments stemming from ZP area mutations
- Addresses mammalian and non-mammalian systems
Read Online or Download A Guide to Zona Pellucida Domain Proteins PDF
Best molecular biology books
The aim of the publication is to provide a survey of the physics that's suitable for organic functions, and in addition to debate what sort of biology wishes physics. The ebook offers a huge account of uncomplicated physics, correct for the functions and numerous functions from homes of proteins to tactics within the phone to wider subject matters comparable to the mind, the starting place of lifestyles and evolution.
A staff of top specialists comprehensively overview and synthesize the newest advances in our realizing of the function of cerebral signaling in neuronal and cerebral functionality. The authors emphasize the sensible position of many of the signaling pathways in reminiscence, apoptosis and degeneration, melancholy, and drug dependence in either well-being and diseased states.
Content material: utilizing organelle markers to explain the heritage, ecology and evolution of plant populations / R. A. Ennos, and . .. [et al. ] -- Isolation inside species and the historical past of glacial refugia / C. Ferris, R. A. King and G. M. Hewitt -- using uniparentally inherited uncomplicated series repeat markers in plant inhabitants reviews and systematics / J.
- BSCS Biology: A Molecular Approach, Student Edition
- Handbook of Computational Molecular Biology
- Methods in Muscle Biology
- On Human Nature. Biology, Psychology, Ethics, Politics, and Religion
Additional resources for A Guide to Zona Pellucida Domain Proteins
Zhao M, Gold L, Dorward H, Liang L et al. Mutation of a conserved hydrophobic patch prevents incorporation of ZP3 into the zona pellucida surrounding mouse oocytes. Mol Cell Biol 23, 8982–8991 (2003). 4 Structure of the ZPD As mentioned previously, the ZPD is a bipartite structure consisting of two sub‐ domains, ZP‐N and ZP‐C, linked by a protease‐sensitive region. However, ZP‐N can serve as an independent structural domain since it is present in ZPD proteins Plac1, Oosp1, and papillote in the absence of the ZP‐C sub‐domain.
Further Reading Bleil JD, Wassarman PM. Structure and function of the zona pellucida: identification and characterization of the proteins of the mouse oocyte’s zona pellucida. Dev Biol 76, 185–202 (1980). Boja ES, Hoodbhoy T, Fales HM, Dean J. Structural characterization of native mouse zona pellucida proteins using mass spectrometry. J Biol Chem 278, 34189–34202 (2003). Bork P. A trefoil domain in the major rabbit zona pellucida protein. Protein Sci 2, 669–670 (1993). Callebaut I, Mornon JP, Monget P.
Mammalian ZP proteins, tectorin‐α, and uromodulin). It is likely that ZP proteins are derived from a common ancestral gene. 2). 7), amphibians, and birds. The absence of ZPd and ZPax in mammals suggests that these genes have been lost during evolution. Accordingly, mammals have three to four ZP genes, amphibians have five ZP genes, and birds have six ZP genes. Since more and more DNA sequencing data has become available, a better understanding of the genetics of the ZP has emerged. , mZP3 vs.
A Guide to Zona Pellucida Domain Proteins by Eveline S. Litscher, Paul M. Wassarman
- Theta-Funktionen und spezielle Weierstraßsche Funktionen by F. Tölke PDF
- Learning Politics From Sivaram: The Life and Death of a by Mark P. Whitaker PDF